ACE inhibitors

Angiotensin-Converting Enzyme (ACE) Inhibitors are commonly prescribed for the treatment of hypertension, and have few side effects.

ACE inhibitors prevent the production of Angiotensin II - a chemical that narrows blood vessels. At the same time, they allow another substance - Bradykinin - to remain in the blood, helping to keep the arteries wide.

ACE Inhibitors affect other conditions as well: They delay kidney diseases, protect against diabetes and prevent some cardiovascular diseases. They are especially important for treating high blood pressure in people with coronary heart disease, heart failure or kidney failure.

Some ACE inhibitors are:

• Captopril
• Benazepril
• Enalapril
• Fosinopril
• Perindopril

ACE inhibitors side effects

ACE inhibitors have few side effects:

• Dry Cough - More frequent in women. If the coughing is persistent and annoying, consult your doctor, who might want to change your medication or give you some cough medicine.
• Swelling of the neck, face and tongue - A rare side effect, that occurs more commonly in blacks and smokers. This condition could be dangerous if swelling obstructs breathing.
• Rashes may appear in rare cases.
• Confusion
• Irregular heartbeat
• Nervousness
• Difficult breathing
• Weakness or heaviness of legs

These last symptoms may be signs of an elevated level of potassium, which could be dangerous if too high. Have your potassium level reguarly tested, and should any of the symptoms occur, call your doctor immediately.

Pregnant women should avoid using ACE inhibitors: They can cause serious birth defects. Nursing mothers should avoid this medication as well.

Children can take ACE inhibitors, but more attention should be given to potential side effects.